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Quantitative Analysis of the Binding of Simian Virus 40 Large T Antigen to DNA
SV40 large T antigen (T-ag) is a multifunctional protein that successively binds to 5′-GAGGC-3′ sequences in the viral origin of replication, melts the origin, unwinds DNA ahead of the replication fork, and interacts with host DNA replication factors to promote replication of the simian virus 40 gen...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951407/ https://ncbi.nlm.nih.gov/pubmed/17596312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00384-07 |
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