TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation.
The ability of the HIV-1 Tat protein to trans -activate HIV-1 transcription in vitro is specifically inhibited by a circular TAR RNA decoy. This inhibition is not overcome by adding an excess of Tat to the reaction but is partially overcome by adding Tat in combination with nuclear extract, suggesti...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4481 |
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