TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation.

The ability of the HIV-1 Tat protein to trans -activate HIV-1 transcription in vitro is specifically inhibited by a circular TAR RNA decoy. This inhibition is not overcome by adding an excess of Tat to the reaction but is partially overcome by adding Tat in combination with nuclear extract, suggesti...

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Publicado en:	Nucleic Acids Res
Autores principales:	Bohjanen, P R, Liu, Y, Garcia-Blanco, M A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4481
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