TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation.

The ability of the HIV-1 Tat protein to trans -activate HIV-1 transcription in vitro is specifically inhibited by a circular TAR RNA decoy. This inhibition is not overcome by adding an excess of Tat to the reaction but is partially overcome by adding Tat in combination with nuclear extract, suggesti...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Bohjanen, P R, Liu, Y, Garcia-Blanco, M A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4481
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