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A nucleolar TAR decoy inhibitor of HIV-1 replication

Tat is a critical regulatory factor in HIV-1 gene expression. It mediates the transactivation of transcription from the HIV-1 LTR by binding to the transactivation response (TAR) element in a complex with cyclin T1. Because of its critical and early role in HIV gene expression, Tat and its interacti...

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Autors principals: Michienzi, Alessandro, Li, Shirley, Zaia, John A., Rossi, John J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137834/
https://ncbi.nlm.nih.gov/pubmed/12376617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212229599
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