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A nucleolar TAR decoy inhibitor of HIV-1 replication

Tat is a critical regulatory factor in HIV-1 gene expression. It mediates the transactivation of transcription from the HIV-1 LTR by binding to the transactivation response (TAR) element in a complex with cyclin T1. Because of its critical and early role in HIV gene expression, Tat and its interacti...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Michienzi, Alessandro, Li, Shirley, Zaia, John A., Rossi, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12376617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212229599
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