Oligonucleotides with conjugated dihydropyrroloindole tripeptides: base composition and backbone effects on hybridization.
The ability of conjugated minor groove binding (MGB) residues to stabilize nucleic acid duplexes was investigated by synthesis of oligonucleotides bearing a tethered dihydropyrroloindole tripeptide (CDPI3). Duplexes bearing one or more of these conjugated MGBs were varied by base composition (AT- or...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
1997
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3718 |
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