Oligonucleotides with conjugated dihydropyrroloindole tripeptides: base composition and backbone effects on hybridization.

The ability of conjugated minor groove binding (MGB) residues to stabilize nucleic acid duplexes was investigated by synthesis of oligonucleotides bearing a tethered dihydropyrroloindole tripeptide (CDPI3). Duplexes bearing one or more of these conjugated MGBs were varied by base composition (AT- or...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Kutyavin, I V, Lukhtanov, E A, Gamper, H B, Meyer, R B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3718
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