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Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o(–) airway epithelial monolayers
The cystic fibrosis transmembrane conductance regulator (CFTR) is a cyclic AMP-regulated chloride channel. Mutations in the CFTR gene result in cystic fibrosis (CF). The most common mutation, ΔF508, results in endoplasmic reticulum-associated degradation (ERAD) of CFTR. ΔF508 CFTR has been described...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Blackwell Science Inc
2005
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464253/ https://ncbi.nlm.nih.gov/pubmed/16210354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.096669 |
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