Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1.

Gelijkaardige items

• The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
  door: Gorman, M A, et al.
  Gepubliceerd in: (1997)
• Recognition of oxidized abasic sites by repair endonucleases.
  door: Häring, M, et al.
  Gepubliceerd in: (1994)
• Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta
  door: Beloglazova, Natalia G., et al.
  Gepubliceerd in: (2004)
• Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity.
  door: Barzilay, G, et al.
  Gepubliceerd in: (1995)
• Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1
  door: Malina, Jaroslav, et al.
  Gepubliceerd in: (2015)