Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1.
HAP1 is a divalent cation-dependent endonuclease from human cells with specificity for apurinic/apyrimidinic (AP) sites in DNA. Extraction of the essential metal ion from purified HAP1 stabilized its binding to an oligonucleotide containing a single AP site, permitting AP site binding studies to be...
Kaydedildi:
| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8932375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.21.4217 |
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