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Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch

Adenine-DNA glycosylase MutY of Escherichia coli catalyzes the cleavage of adenine when mismatched with 7,8-dihydro-8-oxoguanine (GO), an oxidatively damaged base. The biological outcome is the prevention of C/G→A/T transversions. The molecular mechanism of base excision repair (BER) of A/GO in mamm...

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Udgivet i:Nucleic Acids Res
Principais autores: Yang, Hanjing, Clendenin, Wendy M., Wong, Donny, Demple, Bruce, Slupska, Malgorzata M., Chiang, Ju-Huei, Miller, Jeffrey H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.743
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