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Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

Abasic (AP) sites are common, potentially mutagenic DNA damages that are attacked by AP endonucleases. The biological roles of these enzymes in metazoans have not been tested. We have cloned the human cDNA (APE) that encodes the main nuclear AP endonuclease. The predicted Ape protein, which contains...

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Detaylı Bibliyografya
Asıl Yazarlar: Demple, B, Herman, T, Chen, D S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC53153/
https://ncbi.nlm.nih.gov/pubmed/1722334
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