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Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV.

DNA damage generated by oxygen radicals includes base-free apurinic/apyrimidinic (AP) sites and strand breaks that bear deoxyribose fragments. The yeast Saccharomyces cerevisiae repairs such DNA lesions by using a single major enzyme. We have cloned the yeast structural gene (APN1) encoding this AP...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Popoff, S C, Spira, A I, Johnson, A W, Demple, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1693433/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4193
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