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Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

Abasic (AP) sites are common, potentially mutagenic DNA damages that are attacked by AP endonucleases. The biological roles of these enzymes in metazoans have not been tested. We have cloned the human cDNA (APE) that encodes the main nuclear AP endonuclease. The predicted Ape protein, which contains...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Demple, B, Herman, T, Chen, D S
פורמט: Artigo
שפה:Inglês
יצא לאור: 1991
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC53153/
https://ncbi.nlm.nih.gov/pubmed/1722334
תגים: הוספת תג
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