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Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damage in vitro: homology with bacterial repair enzymes.

Ionizing radiation and radiomimetic compounds, such as hydrogen peroxide and bleomycin, generate DNA strand breaks with fragmented deoxyribose 3' termini via the formation of oxygen-derived free radicals. These fragmented sugars require removal by enzymes with 3' phosphodiesterase activity...

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Detaylı Bibliyografya
Asıl Yazarlar: Robson, C N, Milne, A M, Pappin, D J, Hickson, I D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC333785/
https://ncbi.nlm.nih.gov/pubmed/1708495
Etiketler: Etiketle
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