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Hypoxia modulates early events in T cell receptor-mediated activation in human T lymphocytes via Kv1.3 channels
T lymphocytes are exposed to hypoxia during their development and when they migrate to hypoxic pathological sites. Although it has been shown that hypoxia inhibits Kv1.3 channels and proliferation in human T cells, the mechanisms by which hypoxia regulates T cell activation are not fully understood....
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456048/ https://ncbi.nlm.nih.gov/pubmed/15677684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.081893 |
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