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Localization of Kv1.3 channels in the immunological synapse modulates the calcium response to antigen stimulation in T lymphocytes

The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an antigen presenting cell, is essential for the proper development of signaling events including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis in human T cells and m...

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Detalhes bibliográficos
Main Authors: Nicolaou, Stella A., Neumeier, Lisa, Steckly, Ashleigh, Kucher, Vladimir, Takimoto, Koichi, Conforti, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783516/
https://ncbi.nlm.nih.gov/pubmed/19841189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900613
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