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DIFFERENTIAL CALCIUM SIGNALING AND Kv1.3 TRAFFICKING TO THE IMMUNOLOGICAL SYNAPSE IN SYSTEMIC LUPUS ERYTHEMATOSUS

Systemic lupus erythematosus (SLE) T cells exhibit several activation signaling anomalies including defective Ca(2+) response and increased NF-AT nuclear translocation. The duration of the Ca(2+) signal is critical in the activation of specific transcription factors and a sustained Ca(2+) response a...

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Detalhes bibliográficos
Main Authors: Nicolaou, Stella A., Neumeier, Lisa, Takimoto, Koichi, Lee, Susan Molleran, Duncan, Heather J., Kant, Shashi K., Mongey, Anne Barbara, Filipovich, Alexandra H., Conforti, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819652/
https://ncbi.nlm.nih.gov/pubmed/19959227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.11.001
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