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Signalling during hypoxia in human T lymphocytes – critical role of the src protein tyrosine kinase p56Lck in the O(2) sensitivity of Kv1.3 channels

T lymphocytes encounter hypoxia when they migrate to pathological sites such as tumours and wounds. The inability of T cells to provide an efficient defence at these sites can in part be explained by the hypoxic environment. Kv1.3 channels, important components of the T cell activation process are i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Szigligeti, Peter, Neumeier, Lisa, Duke, Eugene, Chougnet, Claire, Takimoto, Koichi, Lee, Susan Molleran, Filipovich, Alexandra H, Conforti, Laura
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Blackwell Science Inc 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779731/
https://ncbi.nlm.nih.gov/pubmed/16600997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109967
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