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Signalling during hypoxia in human T lymphocytes – critical role of the src protein tyrosine kinase p56Lck in the O(2) sensitivity of Kv1.3 channels
T lymphocytes encounter hypoxia when they migrate to pathological sites such as tumours and wounds. The inability of T cells to provide an efficient defence at these sites can in part be explained by the hypoxic environment. Kv1.3 channels, important components of the T cell activation process are i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1779731/ https://ncbi.nlm.nih.gov/pubmed/16600997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109967 |
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