Compound-specific Na(+) channel pore conformational changes induced by local anaesthetics

Upon prolonged depolarizations, voltage-dependent Na(+) channels open and subsequently inactivate, occupying fast and slow inactivated conformational states. Like C-type inactivation in K(+) channels, slow inactivation is thought to be accompanied by rearrangement of the channel pore. Cysteine-label...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Fukuda, Koji, Nakajima, Tadashi, Viswanathan, Prakash C, Balser, Jeffrey R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2005
Teme:
Molecular and Genomic Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456037/
https://ncbi.nlm.nih.gov/pubmed/15677685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.081646
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki