Inhibition of voltage-gated proton channels by local anaesthetics in GMI-R1 rat microglia

NON-TECHNICAL SUMMARY: Lidocaine and bupivacaine are the most commonly used local anaesthetics in clinical practices such as neuraxial anaesthesia and local infiltration. They are known to suppress phagocytosis and the production of reactive oxygen species in immune cells. Voltage-gated proton chann...

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Hlavní autoři: Matsuura, Tadashi, Mori, Takashi, Hasaka, Megumi, Kuno, Miyuki, Kawawaki, Junko, Nishikawa, Kiyonobu, Narahashi, Toshio, Sawada, Makoto, Asada, Akira
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
Neuroscience: Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381313/
https://ncbi.nlm.nih.gov/pubmed/22183729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.218149
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