Inhibition of voltage-gated proton channels by local anaesthetics in GMI-R1 rat microglia

NON-TECHNICAL SUMMARY: Lidocaine and bupivacaine are the most commonly used local anaesthetics in clinical practices such as neuraxial anaesthesia and local infiltration. They are known to suppress phagocytosis and the production of reactive oxygen species in immune cells. Voltage-gated proton chann...

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Main Authors: Matsuura, Tadashi, Mori, Takashi, Hasaka, Megumi, Kuno, Miyuki, Kawawaki, Junko, Nishikawa, Kiyonobu, Narahashi, Toshio, Sawada, Makoto, Asada, Akira
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2012
主題:
Neuroscience: Cellular/Molecular
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381313/
https://ncbi.nlm.nih.gov/pubmed/22183729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.218149
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