載入...
A conserved ring of charge in mammalian Na(+) channels: a molecular regulator of the outer pore conformation during slow inactivation
The molecular mechanisms underlying slow inactivation in sodium channels are elusive. Our results suggest that EEDD, a highly conserved ring of charge in the external vestibule of mammalian voltage-gated sodium channels, undermines slow inactivation. By employing site-directed mutagenesis, we found...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2006
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890405/ https://ncbi.nlm.nih.gov/pubmed/16873407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.115105 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|