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Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
Cardiac myocytes contain two constitutive NO synthase (NOS) isoforms with distinct spatial locations, which allows for isoform-specific regulation. One regulatory mechanism for NOS is substrate (l-arginine) bioavailability. We tested the hypothesis that arginase (Arg), which metabolizes l-arginine,...
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| Hoofdauteurs: | , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450243/ https://ncbi.nlm.nih.gov/pubmed/16537391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506589103 |
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