Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism

Cardiac myocytes contain two constitutive NO synthase (NOS) isoforms with distinct spatial locations, which allows for isoform-specific regulation. One regulatory mechanism for NOS is substrate (l-arginine) bioavailability. We tested the hypothesis that arginase (Arg), which metabolizes l-arginine,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Steppan, Jochen, Ryoo, Sungwoo, Schuleri, Karl H., Gregg, Chris, Hasan, Rani K., White, A. Ron, Bugaj, Lukasz J., Khan, Mehnaz, Santhanam, Lakshmi, Nyhan, Daniel, Shoukas, Artin A., Hare, Joshua M., Berkowitz, Dan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450243/
https://ncbi.nlm.nih.gov/pubmed/16537391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506589103
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky