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OxLDL-Dependent Activation of Arginase II Is Dependent on the LOX-1 Receptor and Downstream RhoA Signaling

AIMS: Arginase II regulates NOS activity by competing for the substrate L-arginine. Oxidized LDL (OxLDL) is a proatherogenic molecule that activates arginase II. We tested the hypotheses that OxLDL-dependent arginase II activation occurs through a specific receptor, and via a Rho GTPase effector mec...

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Detaylı Bibliyografya
Asıl Yazarlar: Ryoo, Sungwoo, Bhunia, Anil, Chang, Fumin, Shoukas, Artin, Berkowitz, Dan E, Romer, Lewis H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031764/
https://ncbi.nlm.nih.gov/pubmed/21130456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.10.044
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