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OxLDL-Dependent Activation of Arginase II Is Dependent on the LOX-1 Receptor and Downstream RhoA Signaling
AIMS: Arginase II regulates NOS activity by competing for the substrate L-arginine. Oxidized LDL (OxLDL) is a proatherogenic molecule that activates arginase II. We tested the hypotheses that OxLDL-dependent arginase II activation occurs through a specific receptor, and via a Rho GTPase effector mec...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031764/ https://ncbi.nlm.nih.gov/pubmed/21130456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.10.044 |
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