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LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Oxidized LDL (oxLDL) promotes lipid accumulation as well as growth and survival signaling in macrophages. OxLDL uptake is mainly due to scavenger receptors SR-AI/II and CD36. However, other scavenger receptors such as lectin-like oxLDL receptor-1 (LOX-1) may also play a role. We used mice with targe...

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Detalles Bibliográficos
Main Authors: Schaeffer, David F., Riazy, Maziar, Parhar, Kuljit S., Chen, Johnny H., Duronio, Vincent, Sawamura, Tatsuya, Steinbrecher, Urs P.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724041/
https://ncbi.nlm.nih.gov/pubmed/19359704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900167-JLR200
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