LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Oxidized LDL (oxLDL) promotes lipid accumulation as well as growth and survival signaling in macrophages. OxLDL uptake is mainly due to scavenger receptors SR-AI/II and CD36. However, other scavenger receptors such as lectin-like oxLDL receptor-1 (LOX-1) may also play a role. We used mice with targe...

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Detaylı Bibliyografya
Asıl Yazarlar: Schaeffer, David F., Riazy, Maziar, Parhar, Kuljit S., Chen, Johnny H., Duronio, Vincent, Sawamura, Tatsuya, Steinbrecher, Urs P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724041/
https://ncbi.nlm.nih.gov/pubmed/19359704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900167-JLR200
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