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LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Oxidized LDL (oxLDL) promotes lipid accumulation as well as growth and survival signaling in macrophages. OxLDL uptake is mainly due to scavenger receptors SR-AI/II and CD36. However, other scavenger receptors such as lectin-like oxLDL receptor-1 (LOX-1) may also play a role. We used mice with targe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schaeffer, David F., Riazy, Maziar, Parhar, Kuljit S., Chen, Johnny H., Duronio, Vincent, Sawamura, Tatsuya, Steinbrecher, Urs P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724041/
https://ncbi.nlm.nih.gov/pubmed/19359704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900167-JLR200
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