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Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1

OBJECTIVE: Neuropathy is a frequent and severe complication of diabetes. Multiple metabolic defects in type 2 diabetic patients result in oxidative injury of dorsal root ganglia (DRG) neurons. Our previous work focused on hyperglycemia clearly demonstrates induction of mitochondrial oxidative stress...

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Main Authors: Vincent, Andrea M., Hayes, John M., McLean, Lisa L., Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Feldman, Eva L.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750230/
https://ncbi.nlm.nih.gov/pubmed/19592619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0047
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