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Apolipoprotein E Knockout as the Basis for Mouse Models of Dyslipidemia-Induced Neuropathy
Dyslipidemia has been identified as an important pathogenic risk factor for diabetic neuropathy, but current animal models do not adequately reproduce the lipid profile observed in human diabetics (increased triglycerides with an elevated LDL-cholesterol and reduced HDL-cholesterol). High fat feedin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534788/ https://ncbi.nlm.nih.gov/pubmed/23059459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.10.002 |
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