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Apolipoprotein E Knockout as the Basis for Mouse Models of Dyslipidemia-Induced Neuropathy

Dyslipidemia has been identified as an important pathogenic risk factor for diabetic neuropathy, but current animal models do not adequately reproduce the lipid profile observed in human diabetics (increased triglycerides with an elevated LDL-cholesterol and reduced HDL-cholesterol). High fat feedin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hinder, Lucy M., Vincent, Andrea M., Hayes, John M., McLean, Lisa L., Feldman, Eva L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534788/
https://ncbi.nlm.nih.gov/pubmed/23059459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.10.002
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