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SOD2 Protects Neurons from Injury in Cell Culture and Animal Models of Diabetic Neuropathy

Hyperglycemia-induced oxidative stress is an inciting event in the development of diabetic complications including diabetic neuropathy. Our observations of significant oxidative stress and morphological abnormalities in mitochondria led us to examine manganese superoxide dismutase (SOD2), the enzyme...

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Detalhes bibliográficos
Main Authors: Vincent, Andrea M., Russell, James W., Sullivan, Kelli A., Backus, Carey, Hayes, John M., McLean, Lisa L., Feldman, Eva L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190625/
https://ncbi.nlm.nih.gov/pubmed/17927981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.07.017
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