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SOD2 Protects Neurons from Injury in Cell Culture and Animal Models of Diabetic Neuropathy

Hyperglycemia-induced oxidative stress is an inciting event in the development of diabetic complications including diabetic neuropathy. Our observations of significant oxidative stress and morphological abnormalities in mitochondria led us to examine manganese superoxide dismutase (SOD2), the enzyme...

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Библиографические подробности
Главные авторы: Vincent, Andrea M., Russell, James W., Sullivan, Kelli A., Backus, Carey, Hayes, John M., McLean, Lisa L., Feldman, Eva L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190625/
https://ncbi.nlm.nih.gov/pubmed/17927981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.07.017
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