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Enzymatic aminoacylation of tRNA with unnatural amino acids
The biochemical flexibility of the cellular translation apparatus offers, in principle, a simple route to the synthesis of drug-like modified peptides and novel biopolymers. However, only ≈75 unnatural building blocks are known to be fully compatible with enzymatic tRNA acylation and subsequent ribo...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450175/ https://ncbi.nlm.nih.gov/pubmed/16537388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509219103 |
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