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Enzymatic aminoacylation of tRNA with unnatural amino acids

The biochemical flexibility of the cellular translation apparatus offers, in principle, a simple route to the synthesis of drug-like modified peptides and novel biopolymers. However, only ≈75 unnatural building blocks are known to be fully compatible with enzymatic tRNA acylation and subsequent ribo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hartman, Matthew C. T., Josephson, Kristopher, Szostak, Jack W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450175/
https://ncbi.nlm.nih.gov/pubmed/16537388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509219103
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