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Ribosomal incorporation of backbone modified amino acids via an editing-deficient aminoacyl-tRNA synthetase

The ability to incorporate non-canonical amino acids (ncAA) using translation offers researchers the ability to extend the functionality of proteins and peptides for many applications including synthetic biology, biophysical and structural studies, and discovery of novel ligands. Here we describe th...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Iqbal, Emil S., Dods, Kara K., Hartman, Matthew C.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993425/
https://ncbi.nlm.nih.gov/pubmed/29367962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob02931d
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