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Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
The tumor suppressor function of PTEN is strongly linked to its ability to dephosphorylate phosphatidylinositol-3,4,5 trisphosphate and, thereby, control cell growth, survival, and migration. However, the mechanism of action of PTEN in living cells is largely unexplored. Here we use single-molecule...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450134/ https://ncbi.nlm.nih.gov/pubmed/16537447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510570103 |
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