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Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

The tumor suppressor function of PTEN is strongly linked to its ability to dephosphorylate phosphatidylinositol-3,4,5 trisphosphate and, thereby, control cell growth, survival, and migration. However, the mechanism of action of PTEN in living cells is largely unexplored. Here we use single-molecule...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vazquez, Francisca, Matsuoka, Satomi, Sellers, William R., Yanagida, Toshio, Ueda, Masahiro, Devreotes, Peter N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450134/
https://ncbi.nlm.nih.gov/pubmed/16537447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510570103
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