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Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions

The molecular mechanisms that underlie asymmetric PTEN distribution at the posterior of polarized motile cells and regulate anterior pseudopod formation were addressed by novel single-molecule tracking analysis. Heterogeneity in the lateral mobility of PTEN on a membrane indicated the existence of t...

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Detalhes bibliográficos
Main Authors: Matsuoka, Satomi, Shibata, Tatsuo, Ueda, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542079/
https://ncbi.nlm.nih.gov/pubmed/23326224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002862
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