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Sodium Nitroprusside Promotes IRP2 Degradation via an Increase in Intracellular Iron and in the Absence of S Nitrosylation at C178

In iron-replete cells the posttranscriptional regulator IRP2 undergoes ubiquitination and proteasomal degradation. A similar response occurs in cells exposed to sodium nitroprusside (SNP), an NO-releasing drug. It has been proposed that nitroprusside ([Fe(CN)(5)NO](2−)) fails to donate iron into cel...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wang, Jian, Fillebeen, Carine, Chen, Guohua, Andriopoulos, Bill, Pantopoulos, Kostas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430246/
https://ncbi.nlm.nih.gov/pubmed/16479012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1948-1954.2006
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