Llwytho...
Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity
BACKGROUND: Iron regulatory protein 2 (IRP2), a post-transcriptional regulator of cellular iron metabolism, undergoes iron-dependent degradation via the ubiquitin-proteasome pathway. A stretch of 73 amino acids within the N-terminal domain 1 of the protein was reported to function as an iron sensor....
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267205/ https://ncbi.nlm.nih.gov/pubmed/18226225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-15 |
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