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Electrophoretic Mobility Shift Assay (EMSA) for the Study of RNA-Protein Interactions: The IRE/IRP Example

RNA/protein interactions are critical for post-transcriptional regulatory pathways. Among the best-characterized cytosolic RNA-binding proteins are iron regulatory proteins, IRP1 and IRP2. They bind to iron responsive elements (IREs) within the untranslated regions (UTRs) of several target mRNAs, th...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Fillebeen, Carine, Wilkinson, Nicole, Pantopoulos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396942/
https://ncbi.nlm.nih.gov/pubmed/25548934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52230
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