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The IRP/IRE system in vivo: insights from mouse models

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) post-transcriptionally control the expression of several mRNAs encoding proteins of iron, oxygen and energy metabolism. The mechanism involves their binding to iron responsive elements (IREs) in the untranslated regions of target mRNAs, thereby contro...

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Detalhes bibliográficos
Main Authors: Wilkinson, Nicole, Pantopoulos, Kostas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112806/
https://ncbi.nlm.nih.gov/pubmed/25120486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00176
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