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Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts
Iron is essential for proliferation of normal and neoplastic cells. Cellular iron uptake, utilization and storage are regulated by transcriptional and post-transcriptional mechanisms. We hypothesized that the disruption of iron homeostasis may modulate the growth properties of cancer cells. To addre...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925110/ https://ncbi.nlm.nih.gov/pubmed/17127713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgl210 |
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