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Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts

Iron is essential for proliferation of normal and neoplastic cells. Cellular iron uptake, utilization and storage are regulated by transcriptional and post-transcriptional mechanisms. We hypothesized that the disruption of iron homeostasis may modulate the growth properties of cancer cells. To addre...

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Библиографические подробности
Главные авторы: Chen, Guohua, Fillebeen, Carine, Wang, Jian, Pantopoulos, Kostas
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925110/
https://ncbi.nlm.nih.gov/pubmed/17127713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgl210
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