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Hepatitis C Virus Infection Causes Iron Deficiency in Huh7.5.1 Cells

Patients with chronic hepatitis C virus (HCV) infection frequently develop systemic iron overload, which exacerbates morbidity. Nevertheless, iron inhibits HCV replication in cell culture models and thereby exerts antiviral activity. We hypothesized that the cellular iron status is crucial for the e...

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Bibliographic Details
Main Authors: Fillebeen, Carine, Pantopoulos, Kostas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862679/
https://ncbi.nlm.nih.gov/pubmed/24349485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083307
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