Quadruple Mutations in Dihydrofolate Reductase of Plasmodium falciparum Isolates from Car Nicobar Island, India

Quadruple mutations in the Plasmodium falciparum dihydrofolate reductase (PFDHFR) enzyme give rise to the highest level of pyrimethamine resistance leading to treatment failures. We describe here the presence of these quadruple mutations in a majority of P. falciparum isolates from Car Nicobar (Anda...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ahmed, Anwar, Das, Manoj K., Dev, Vas, Saifi, Muheet A., Wajihullah, Sharma, Yagya D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426982/
https://ncbi.nlm.nih.gov/pubmed/16569880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1546-1549.2006
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