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Multiple Origins of Plasmodium falciparum Dihydropteroate Synthetase Mutant Alleles Associated with Sulfadoxine Resistance in India

With the spread of chloroquine (CQ)-resistant malaria in India, sulfadoxine-pyrimethamine (SP) alone or in combination with artesunate is used as an alternative antimalarial drug. Due to continuous drug pressure, the Plasmodium falciparum parasite is exhibiting resistance to antifolates because of m...

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Detalhes bibliográficos
Main Authors: Lumb, Vanshika, Das, Manoj K., Singh, Neeru, Dev, Vas, Khan, Wajihullah, Sharma, Yagya D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101454/
https://ncbi.nlm.nih.gov/pubmed/21422213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01151-10
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