Quadruple Mutations in Dihydrofolate Reductase of Plasmodium falciparum Isolates from Car Nicobar Island, India

Quadruple mutations in the Plasmodium falciparum dihydrofolate reductase (PFDHFR) enzyme give rise to the highest level of pyrimethamine resistance leading to treatment failures. We describe here the presence of these quadruple mutations in a majority of P. falciparum isolates from Car Nicobar (Anda...

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Bibliografiska uppgifter
Huvudupphovsmän: Ahmed, Anwar, Das, Manoj K., Dev, Vas, Saifi, Muheet A., Wajihullah, Sharma, Yagya D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426982/
https://ncbi.nlm.nih.gov/pubmed/16569880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1546-1549.2006
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