Quadruple Mutations in Dihydrofolate Reductase of Plasmodium falciparum Isolates from Car Nicobar Island, India

Quadruple mutations in the Plasmodium falciparum dihydrofolate reductase (PFDHFR) enzyme give rise to the highest level of pyrimethamine resistance leading to treatment failures. We describe here the presence of these quadruple mutations in a majority of P. falciparum isolates from Car Nicobar (Anda...

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Bibliografiske detaljer
Main Authors: Ahmed, Anwar, Das, Manoj K., Dev, Vas, Saifi, Muheet A., Wajihullah, Sharma, Yagya D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426982/
https://ncbi.nlm.nih.gov/pubmed/16569880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1546-1549.2006
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