Загрузка...
Mutant Huntingtin: Nuclear translocation and cytotoxicity mediated by GAPDH
The pathophysiology of Huntington’s disease reflects actions of mutant Huntingtin (Htt) (mHtt) protein with polyglutamine repeats, whose N-terminal fragment translocates to the nucleus to elicit neurotoxicity. We establish that the nuclear translocation and associated cytotoxicity of mHtt reflect a...
Сохранить в:
| Главные авторы: | , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413934/ https://ncbi.nlm.nih.gov/pubmed/16492755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511316103 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|