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Specific functional interactions of nucleotides at key (−)3 and (+)4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex
Eukaryotic initiation factor (eIF) 1 maintains the fidelity of initiation codon selection and enables mammalian 43S preinitiation complexes to discriminate against AUG codons with a context that deviates from the optimum sequence GCC(A/G)CC AUGG, in which the purines at (−)3 and (+)4 positions are m...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1410799/ https://ncbi.nlm.nih.gov/pubmed/16510876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1397906 |
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