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DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context
During eukaryotic translation initiation, the 43S preinitiation complex (43S PIC), consisting of the 40S ribosomal subunit, eukaryotic initiation factors (eIFs) and initiator tRNA scans mRNA to find an appropriate start codon. Key roles in the accuracy of initiation codon selection belong to eIF1 an...
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Udgivet i: | Nucleic Acids Res |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872109/ https://ncbi.nlm.nih.gov/pubmed/27067542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw240 |
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